Timolol andriol testosterone penetrates the cornea of the eye tissue. The small amount reaches the systemic circulation by absorption through the conjunctiva, the mucous membranes of the nose and the lachrymal tract. Excretion of buy deca durabolin online metabolites – the kidneys. In infants and young children the concentration of the active substance substantially exceeds its plasma Cmax in adults.
Open-angle glaucoma, secondary glaucoma (uveal, afakicheskaya, posttraumatic), a sharp rise in intraocular pressure, angle-closure glaucoma (in combination with miotikami).
Bronchial asthma, sinus bradycardia, AV block II-III century., Acute and chronic heart failure, cardiogenic shock, degenerative corneal disease, rhinitis, hypersensitivity to the drug, children under 1 year.
Application with caution chronic obstructive pulmonary disease, severe course , cerebrovascular disease, chronic heart failure, pulmonary insufficiency, diabetes, hypoglycemia, hyperthyroidism, myasthenia gravis, concurrent administration of other beta-blockers, hypotension, sinoatrial block.
Pregnancy and lactation
During pregnancy, drug use, if the expected benefit to the mother outweighs the potential risk to the fetus. During the use of the drug should stop breastfeeding.
Dosage and administration
Adults and children buried in the conjunctival sac of one drop of 0.25% solution over 1 year, 2 times a day, the lack of effectiveness – 1 drop of 0.5% solution of 2 times a day. When intraocular buy deca durabolin online pressure normalizing the maintenance dose – 1 drop of 0.25% 1 per day.
Local reactions: redness eyelid skin, burning and itching in the eyes, conjunctival hyperemia, tearing or decrease lacrimation, photophobia, edema of the corneal epithelium, a short break in visual acuity;blepharitis, conjunctivitis, long-term use may develop superficial punctate keratopathy (reduced corneal transparency) and decreased corneal sensitivity, possible ptosis, rarely – diplopia.
Systemic reactions: paresthesia, rhinitis, nasal congestion, nasal bleeding, decreased blood pressure, bradycardia, bradyarrhythmia, AV block, heart failure, cardiac arrest; andriol testosterone reduction in myocardial contractility, chest pain, dizziness, headache, drowsiness, hallucinations, muscle weakness, sexual dysfunction, decreased potency, transient ischemic attack, collapse, depression; dyspnea, bronchospasm, pulmonary insufficiency; nausea, vomiting, diarrhea, allergic reactions (including urticaria).
When applied topically in the recommended dose overdose symptoms are not observed. In case of accidental ingestion may develop the following symptoms: nausea, vomiting, dizziness, headache, decreased blood pressure, bronchospasm, bradycardia. In case of overdose symptomatic treatment of symptoms. Isoprenaline can be administered intravenously to correct bradycardia or bronchospasm, dobutamine to treat hypotension.
Interaction with other drugs
Epinephrine, pilocarpine, systemic beta-blockers increase the effect. ^ When applying with reserpine – may develop bradycardia or hypotension (this combination requires careful medical supervision); with calcium channel blockers or cardiac glycosides – may impair AV conduction, acute left ventricular failure or hypotension. It enhances the action of muscle relaxants (timolol should be canceled 48 hours before the expected general anesthesia with the use of peripheral muscle relaxants). You can not simultaneously be used with LC antipsychotic (neuroleptics) and anxiolytic the JIC (tranquilizers). During treatment is not recommended to take ethanol (perhaps a sharp decrease in blood pressure).
control effectiveness should be approximately 3-4 weeks after start of treatment *. During treatment at least 1 time in 6 months should monitor the function of tearing, the integrity of the cornea, the field of view.
In the period of treatment must be careful when driving and busy with other potentially hazardous activities that require high concentration * psychomotor speed reactions and good vision ( for 0.5 h. after instillation into the eye.
during treatment should avoid wearing soft contact lenses because of the content in the preservative benzalkonium chloride solution. Hard contact lenses should be removed before instillation and wear no earlier than 15 minutes after.
not should be instilled buy deca durabolin online into the eyes of two beta-blocker at the same time.
with prolonged use may weaken the effect of timolol.
When transferring patients to treatment with timolol may need refractive error correction.
Before andriol testosterone the upcoming surgery with general anesthesia – a drug for 48 hours to cancel. treatment for male hypogonadism cheapest hcg therapy for low testosterone