buy andriol testocaps

It has no intrinsic sympathomimetic and membrane stabilizing activity.
When applied topically as eye drops reduce both normal and elevated intraocular pressure by decreasing the formation of intraocular fluid. It has no effect on pupil size and accommodation.
The action of the drug is 20 buy andriol testocaps minutes after instillation in the conjunctival cavity. The maximum decrease in intraocular pressure occurs within 1-2 hours and lasts for 24 hours.

The local application of timolol maleate rapidly penetrates the cornea. After instillation deca durabolin reviews of eye drops maximum concentration of timolol in the aqueous humor of the anterior chamber is achieved in 1-2 hours.
The small amount reaches the systemic circulation by absorption throughФ the vessels of the conjunctiva, nasal mucosa and lacrimal tract. Withdrawal timolol metabolites is carried out mainly by the kidneys.
In infants and young children the concentration of the active substance substantially exceeds its plasma Cmax in adults.

Indications for use :

 

  • increased intraocular pressure (ocular hypertension);
  • open-angle glaucoma;
  • afakicheskaya glaucoma and secondary glaucoma other;
  • as an additional means for reducing the intraocular pressure in angle-closure glaucoma (in combination with miotikami);
  • congenital glaucoma (with failure of other therapeutic measures).Contraindications :
    Do not use the drug “Okupres-E”, if the previously mentioned increased individual sensitivity to timolol. The drug is also contraindicated in patients with a history of the following diseases are present:
  • asthma or other severe chronic obstructive airway disease;
  • sinus bradycardia;
  • atrioventricular block II or III degree;
  • severe heart failure;
  • cardiogenic shock;
  • allergic reaction with generalized skin rash;
  • severe atrophic rhinitis;
  • corneal dystrophy.”Okupres-E” should be used with caution in patients with pulmonary insufficiency, severe cerebrovascular insufficiency, heart failure, diabetes, hypoglycemia, thyrotoxicosis, myasthenia gravis, and while the appointment of other beta-blockers.Pregnancy and lactation :
    Sufficient experience with the use of the drug during pregnancy, lactation and children do not have, however, shown that timolol passes the placental barrier and enters the breast milk. Perhaps the use of the drug “Okupres-E” for the treatment buy andriol testocaps of children, pregnant women and nursing mothers if the expected therapeutic effect is greater than the risk of possible side effects.
    If the drug is used just before birth or during breastfeeding, the newborn should be closely monitored for several days after birth and throughout the entire treatment period, lactating mothers drug “Okupres-E.”Dosage and administration :
    In the beginning of therapy instilled 1 drop drug “Okupres-E ‘of 0.25% and 0.5% in the diseased eye 2 times a day.
    If the intraocular pressure is normal with regular use, you should reduce the dosage – one drop once daily.
    Treatment with “Okupres-E” is held typically for an extended time. Suspension or change the dosage are carried out only by order of the physician.Side effects : Local reactions: irritation and redness of the conjunctiva, eyelid skin, burning and itchy eyes, watery eyes, photophobia, edema of the corneal epithelium, superficial punctate keratopathy, corneal gipostezii, diplopia, ptosis, dry eyes. During deca durabolin reviews the fistuliziruyuschih antiglaukomatoznyh operations may develop detachment of the choroid in the postoperative period. Systemic reactions: Cardio-vascular system: congestive heart failure, bradycardia, bradyarrhythmia, decreased blood pressure, collapse, atrioventricular block, heart failure, transient ischemic attacks. From the respiratory system: dyspnea, bronchospasm, pulmonary insufficiency. On the part of the central nervous system: headache, dizziness, weakness, depression, paresthesia. On the part of the gastrointestinal tract: nausea, diarrhea. Allergic reactions: urticaria, eczema. Rhinitis, sexual dysfunction , alopecia. Topical application may lead to apnea in infants. In case of side effects, discontinue use of the drug and how to contact your doctor as soon as possible (ophthalmologist).Overdose :
    Perhaps the development obscherezorbtivnyh effects typical of beta-blockers: dizziness, headache, arrhythmia, bradycardia, bronchospasm, nausea, vomiting.
    Treatment: Immediately rinse eyes with water or saline solution, symptomatic therapy.

    Interaction with other drugs :
    Co-administration of the drug “Okupresa-E” with eye drops containing epinephrine may cause pupil dilation.
    The specific effect of the drug – reducing intraocular pressure -usilivaetsya while using eye drops containing epinephrine and pilocarpine, burying eyes two beta-blockers should not be.
    Lowering blood pressure and slowing heart rate may potentiate the joint application of the drug with blockers of slow calcium channels, reserpine and other beta-blockers.
    Concomitant use with buy andriol testocaps insulin or oral antidiabetic agents may cause hypoglycemia.
    timolol increases the effects of peripheral muscle relaxants therefore requires removal of the drug 48 hours before planned surgery with general anesthesia.
    this data may also apply to drugs that have been used shortly before.

    Special instructions :
    . You must see your doctor regularly to measure intraocular pressure and corneal examination
    If the patient wears soft contact lenses, he should not use eye drops “Okupres-E ‘of 0.25% and 0.5% as a preservative may be deposited in soft contact lenses and may have adverse effects on the eye tissue.
    it should remove hard contact lenses prior to instillation of the drug and to wear them again only after 15 minutes.
    Immediately after instillation of the drug may reduce the clarity of vision and slow mental reactions, which may reduce the ability to actively participate in street movement, maintenance of machines, or to perform work without reliable deca durabolin reviews support. In an even greater extent this is the case, while the use of the drug with alcohol.
    When transferring patients to treatment with timolol may need refractive error correction after effects caused by previously used miotikami.
    In the case of the upcoming surgery with general anesthesia, it is necessary to cancel the drug for 48 hours.

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